SDHD Human shRNA Plasmid Kit (Locus ID 6392)
Specifications
| Product Data | |
| Locus ID | 6392 |
|---|---|
| Synonyms | CBT1; CII-4; CWS3; cybS; MC2DN3; PGL; PGL1; QPs3; SDH4 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | SDHD - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 6392). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001276503, NM_001276504, NM_001276506, NM_003002, NR_077060, NM_003002.1, NM_003002.2, NM_003002.3, NM_001276503.1, NM_001276504.1, NM_001276506.1, BC009574, BC009574.1, BC005263, BC012603, BC015188, BC015992, BC022350, BC070307, BC071755, BC071756, NM_001276506.2, NM_001276503.2, NM_001276504.2, NM_003002.4 |
| UniProt ID | O14521 |
| Summary | This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants. provided by RefSeq, Feb 2013 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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