SDHD Rabbit Polyclonal Antibody

SKU
TA359351
SDHD Antibody - N-terminal region
  $585.00
5 Days*
Bulk/Customize
Specifications
Specifications
Product Data
Application WB
Reactivity Human
Antibody Host Rabbit
Clonality Polyclonal
Immunogen The immunogen is a synthetic peptide directed towards the N-terminal region of Human SDHD
Specificity Expected reactivity: Human
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration lot specific
Purification Affinity Purified
Conjugation Unconjugated
Storage For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 17kDa
Gene Name succinate dehydrogenase complex subunit D
Database Link
Background This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants.
Synonyms CBT1; CII-4; CybS; PGL; PGL1; QPs3; SDH4
Reference Data
Protein Categories Cancer: Endocrine, Cancer: Gastrointestinal, Intracellular Proteins, Membrane Proteins
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