MICALL2 Human shRNA Plasmid Kit (Locus ID 79778)

SKU TL307289

MICALL2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 79778
• Synonyms: FLJ23471; FLJ23471, FLJ44858; FLJ41996; FLJ44858; FLJ45410; JRAB; junctional Rab13-binding protein; MGC46023; MICAL-L2; MICAL-like 2
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: MICALL2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 79778). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: NM_024723, NM_182924, NM_182924.1, NM_182924.2, NM_182924.3, NM_024723.1, BC037988, BC037988.1, BC039886, NM_182924.4
• UniProt ID: Q8IY33
• Summary: Effector of small Rab GTPases which is involved in junctional complexes assembly through the regulation of cell adhesion molecules transport to the plasma membrane and actin cytoskeleton reorganization. Regulates the endocytic recycling of occludins, claudins and E-cadherin to the plasma membrane and may thereby regulate the establishment of tight junctions and adherens junctions. In parallel, may regulate actin cytoskeleton reorganization directly through interaction with F-actin or indirectly through actinins and filamins. Most probably involved in the processes of epithelial cell differentiation, cell spreading and neurite outgrowth (By similarity).[UniProtKB/Swiss-Prot Function]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient