ABCD4 Human shRNA Plasmid Kit (Locus ID 5826)

SKU TL306917

ABCD4 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 5826
• Synonyms: ABC41; EST352188; MAHCJ; P70R; P79R; PMP69; PXMP1L
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: ABCD4 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 5826). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: NM_005050, NM_020323, NM_020324, NM_020325, NM_020326, NR_003256, NM_001353591, NM_001353592, NM_001353593, NM_001353594, NM_001353595, NM_001353596, NM_001353597, NM_001353598, NM_001353599, NM_001353600, NM_001353601, NM_001353602, NM_001353603, NM_001353604, NM_001353605, NM_001353606, NM_001353607, NM_001353608, NM_001353609, NM_001353610, NR_148466, NR_148467, NR_148468, NR_148469, NR_148470, NR_148471, NR_148472, NR_148473, NR_148474, NM_005050.1, NM_005050.2, NM_005050.3, NM_020323.1, NM_020324.1, NM_020325.1, NM_020326.2, BC012815, BC012815.2, BM667379, NM_005050.4
• UniProt ID: O14678
• Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in several protein-coding and non-protein-coding variants. [provided by RefSeq, Jul 2017]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient