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ABCG1 Human shRNA Plasmid Kit (Locus ID 9619)

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SKU
TL306915
ABCG1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Other products for "ABCG1 or NM_004915"

Specifications
Specifications
Product Data
Locus ID 9619
Synonyms ABC8; WHITE1
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components ABCG1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 9619). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_004915, NM_016818, NM_207174, NM_207627, NM_207628, NM_207629, NM_207630, NM_016818.1, NM_016818.2, NM_207174.1, NM_004915.1, NM_004915.2, NM_004915.3, NM_207627.1, NM_207630.1, BC029158, BC029158.1, NM_016818.3
UniProt ID P45844
Summary The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Monitoring the itinerary of lysosomal cholesterol in Niemann-Pick Type C1-deficient cells after cyclodextrin treatment
Feltes, Gale, Moores et al
J. Lipid Res. (2020)
AI Summary: OriGene's shRNA plasmids targeting ABCA1 and ABCG1 were used to generate stable knockdown cell lines, enabling the study of cholesterol trafficking pathways in Niemann-Pick Type C1-deficient cells.
Snippet: For stable knockdown of ABCA1, or ABCG1, shRNA plasmids were obtained from Origene and used to produce lentivirus in HEK 293T cells according to the TransIT -Lenti protocol using TransIT -Lenti transfection reagent and Mission Lentiviral Packaging Mix
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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