KIF7 Human shRNA Plasmid Kit (Locus ID 374654)
Specifications
| Product Data | |
| Locus ID | 374654 |
|---|---|
| Synonyms | ACLS; AGBK; HLS2; JBTS12; UNQ340 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | KIF7 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 374654). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_198525, NM_198525.1, NM_198525.2, BC040878, BC042063, BC104044, BC112271, BC112273, BC143461, NM_198525.3 |
| UniProt ID | Q2M1P5 |
| Summary | This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies. provided by RefSeq, Oct 2011 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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