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KIF7 Mouse Monoclonal Antibody [Clone ID: 2A7-10B8-9A9]

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SKU
TA384607
KIF7 (2A7) Mouse monoclonal Antibody
Size:
100 ul
Conjugation:
Unconjugated
  $380.00
4 Weeks*
Bulk/Customize

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Specifications
Specifications
Product Data
Clone Name 2A7-10B8-9A9
Application ICC, IHC
Recommended Dilution IHC:1/50-100
ICC/IF:1/50-200
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Synthetic Peptide of Kif 7
Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
Concentration lot specific
Purification Affinity Purified
Conjugation Unconjugated
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Stability 1 year
Shipping Blue Ice
Gene Name kinesin family member 7
Database Link
Background Swiss-Prot Acc.Q2M1P5.Essential for hedgehog signaling regulation: acts as both a negative and positive regulator of sonic hedgehog (Shh) and Indian hedgehog (Ihh) pathways, acting downstream of SMO, through both SUFU-dependent and -independent mechanisms (PubMed:21633164). Involved in the regulation of microtubular dynamics. Required for proper organization of the ciliary tip and control of ciliary localization of SUFU-GLI2 complexes . Required for localization of GLI3 to cilia in response to Shh. Negatively regulates Shh signaling by preventing inappropriate activation of the transcriptional activator GLI2 in the absence of ligand. Positively regulates Shh signaling by preventing the processing of the transcription factor GLI3 into its repressor form. In keratinocytes, promotes the dissociation of SUFU-GLI2 complexes, GLI2 nuclear translocation and Shh signaling activation . Involved in the regulation of epidermal differentiation and chondrocyte development .
Synonyms EQYK340; MGC120653; MGC138476; MGC138478; UNQ340
Reference Data
Protein Categories Intracellular Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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