NADPH oxidase 4 (NOX4) Human shRNA Plasmid Kit (Locus ID 50507)

SKU TL302911

NOX4 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 50507
• Synonyms: KOX; KOX-1; RENOX
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: NOX4 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 50507). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: BC040105, NM_001143836, NM_001143837, NM_001291926, NM_001291927, NM_001291929, NM_001300995, NM_016931, NR_026571, NR_120406, NM_016931.1, NM_016931.2, NM_016931.3, NM_016931.4, NM_001143836.1, NM_001143836.2, NM_001143837.1, NM_001291926.1, NM_001300995.1, NM_001291929.1, NM_001291927.1, BC040105.1, BC051371
• UniProt ID: Q9NPH5
• Summary: This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient