OGT Human shRNA Plasmid Kit (Locus ID 8473)
SKU
TL302811
OGT - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 8473 |
|---|---|
| Synonyms | HRNT1, FLJ23071, MGC22921, O-GLCNAC |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | OGT - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 8473). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_003605, NM_181672, NM_181673, NM_181672.1, NM_181672.2, NM_181673.1, NM_181673.2, NM_003605.2, BC038180, BC038180.1, BC014434, BC015144, NM_181672.3, NM_181673.3 |
| UniProt ID | O15294 |
| Summary | This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. provided by RefSeq, Oct 2009 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Chromatin-associated OGT promotes the malignant progression of hepatocellular carcinoma by activating ZNF263
Wang, Li, Zhou et al
Oncogene (2023)
Wang, Li, Zhou et al
Oncogene (2023)
Cited by 17
AI Summary: OriGene products, specifically lentiviral shRNA plasmids targeting OGT (TL302811V), ZNF263 (TL308199V), and DOCK7 (TL304933V), were used for gene knockdown experiments to investigate the roles of these genes in hepatocellular carcinoma progression.
Snippet: … Although dysregulation of the sole enzyme O- Save;Lentiviral shRNA plasmids for OGT (#sc-40780-V, Santa Cruz;#TL302811V, OriGene Technologies), ZNF263 (#sc-92999-V, Santa Cruz;#TL308199V, OriGene Technologies), DOCK7 (#sc-88434-V, Santa Cruz;#TL304933V, OriGene Technologies) were used for gene knockdown. …
O-GlcNAcylation Enhances NUSAP1 Stability and Promotes Bladder Cancer Aggressiveness
Chen, Liu, Zhang et al
Onco Targets Ther (2021) 14, 445-454 DOI: 10.2147/OTT.S258175
Chen, Liu, Zhang et al
Onco Targets Ther (2021) 14, 445-454 DOI: 10.2147/OTT.S258175
AI Summary: In this study, OriGene’s shRNAs targeting the human OGT gene (No. TR30023) and their controls were used to knock down OGT expression, helping to demonstrate the role of O-GlcNAcylation in promoting NUSAP1 stability and bladder cancer aggressiveness.
Snippet: …The shRNAs (No.TR30023) targeting human OGT gene and their controls were purchased from Origene (CA, USA);- Cell Transfection. … The shRNAs (No.TR30023) targeting human OGT gene and their controls were purchased from Origene (CA, USA)
Showing 1-2 of 2 papers.
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