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RNF111 Human shRNA Plasmid Kit (Locus ID 54778)

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SKU
TL301978
RNF111 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*

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Other products for "RNF111 or NM_001270528"

Specifications
Specifications
Product Data
Locus ID 54778
Synonyms ARK; hRNF111
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components RNF111 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 54778). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001270528, NM_001270529, NM_001270530, NM_017610, NM_001330331, NM_017610.1, NM_017610.2, NM_017610.3, NM_017610.4, NM_017610.5, NM_017610.6, NM_017610.7, NM_001270529.1, NM_001270530.1, NM_001270528.1, BC060862, BC010369, BC020984, BM986870, NM_001270529.2, NM_001270528.2, NM_017610.8
UniProt ID Q6ZNA4
Summary The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. provided by RefSeq, Jul 2012
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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