KDM6A Human shRNA Plasmid Kit (Locus ID 7403)

SKU
TL300596
KDM6A - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 7403
Synonyms bA386N14.2; KABUK2; UTX
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components KDM6A - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 7403). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001291415, NM_001291416, NM_001291417, NM_001291418, NM_001291421, NM_021140, NR_111960, NM_021140.1, NM_021140.2, NM_021140.3, NM_001291421.1, NM_001291418.1, NM_001291417.1, NM_001291416.1, NM_001291415.1, BC093868, BC093868.1, BC113381, BC143272, BC143275, BC143277, BC143278, NM_001291415.2
UniProt ID O15550
Summary This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3. Multiple alternatively spliced transcript variants have been found for this gene. provided by RefSeq, Apr 2014
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

MBD3/NuRD loss participates with KDM6A program to promote DOCK5/8 expression and Rac GTPase activation in human acute myeloid leukemia
Biswas, Chatterjee, Boila et al
FASEB J. (2019)
AI Summary: OriGene’s full-length KDM6A plasmid (RC210861L4) was used in this study to transiently transfect 293T cells, enabling investigation of KDM6A’s role in regulating DOCK5/8 expression and Rac GTPase activation in acute myeloid leukemia.
Snippet: 293T cells were transiently transfected with plasmids containing full-length KDM6A (RC210861L4;OriGene Technologies, Rockville, MD, USA), and KDM6A was isolated using co-immunoprecipitation using 10 mg of antibody against KDM6A (A302-374A;Bethyl Laboratories
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