Nde1 Mouse shRNA Plasmid (Locus ID 67203)

SKU
TG515062
Nde1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 67203
Synonyms 2810027M15Rik; AU042936; AW822251; mNudE; Nude
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components Nde1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 67203). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq BC023267, NM_001114085, NM_001285503, NM_001285504, NM_023317, NM_023317.1, NM_023317.2, NM_001114085.1, NM_001285504.1, NM_001285503.1
UniProt ID Q9CZA6
Summary Required for centrosome duplication and formation and function of the mitotic spindle. Essential for the development of the cerebral cortex. May regulate the production of neurons by controlling the orientation of the mitotic spindle during division of cortical neuronal progenitors of the proliferative ventricular zone of the brain. Orientation of the division plane perpendicular to the layers of the cortex gives rise to two proliferative neuronal progenitors whereas parallel orientation of the division plane yields one proliferative neuronal progenitor and a post-mitotic neuron. A premature shift towards a neuronal fate within the progenitor population may result in an overall reduction in the final number of neurons and an increase in the number of neurons in the deeper layers of the cortex.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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