Pramel7 Mouse shRNA Plasmid (Locus ID 347712)
SKU
TG513619
Pramel7 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
$883.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 347712 |
|---|---|
| Synonyms | AA675346; C81180 |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Format | Retroviral plasmids |
| Components | Pramel7 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 347712). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | BC052825, NM_178250, NM_178250.1, NM_178250.2 |
| UniProt ID | Q810Y8 |
| Summary | Promotes maintenance and self-renewal of pluripotent embryonic stem cells (ESCs), downstream of LIF/STAT3 (PubMed:21425410). Maintains the pluripotency state of ESCs by repressing DNA methylation through the regulation of UHRF1 stability. Mediates the proteasomal degradation of UHRF1. Is required for the establishment of the blastocyst (PubMed:28604677).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Shipping | Ambient |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.