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Ppard Mouse shRNA Plasmid (Locus ID 19015)

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SKU
TG501712
Ppard - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 19015
Synonyms Nr1c2; NUC-1; NUC1; PPAR-beta; PPAR-delta; Pparb; Pparb/d; PPARdelta; PPARb
Vector pGFP-V-RS
E. coli Selection Kanamycin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Ppard - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 19015). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq BC070398, NM_011145, NM_011145.1, NM_011145.2, NM_011145.3
UniProt ID P35396
Summary Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand (By similarity).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Exercise Training-Induced PPARβ Increases PGC-1α Protein Stability and Improves Insulin-Induced Glucose Uptake in Rodent Muscles
Park, Holloszy, Kim et al
Nutrients (2020) 12 (3) DOI: 10.3390/nu12030652
Cited by 26
AI Summary: OriGene contributed shPPARβ and scrambled shRNA (Scr) products, which were used to knock down PPARβ expression in myotubes to study its role in exercise-induced protein stability and glucose uptake.
Snippet: as previously described [6]. Briefly, PPARβ cDNA was amplified via PCR and inserted into the pcDNA 3.1 vector (Thermo Fisher Scientific) to generate the overexpression vector, and shPPARβ and scrambled shRNA (Scr) were purchased from Origene (Rockvile, MD Cached
Metastasis regulation by PPARD expression in cancer cells
Zuo, Xu, Xu et al
JCI Insight (2017) 2 (1), e91419 DOI: 10.1172/jci.insight.91419
AI Summary: OriGene contributed to this study by providing four PPARD-shRNA plasmids (in the pGFP-V-RS vector), which were used to specifically downregulate PPARD expression in cancer cells and investigate its role in metastasis.
Snippet: Plasmid transfections: Four PPARD-shRNA plasmids against mouse PPARD in pGFP-V-RS vector were purchased from Origene. The PPARD shRNA sequences were as follows: shRNA-A,
Showing 1-2 of 2 papers.
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