PPAR delta (PPARD) Human shRNA Plasmid Kit (Locus ID 5467)

SKU
TG320247
PPARD - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 5467
Synonyms FAAR; NR1C2; NUC1; NUCI; NUCII; PPARB
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components PPARD - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 5467). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001171818, NM_001171819, NM_001171820, NM_006238, NM_177435, NM_006238.1, NM_006238.2, NM_006238.3, NM_006238.4, NM_177435.1, NM_177435.2, NM_001171820.1, NM_001171819.1, NM_001171818.1, BC002715, BC007578, BC127809, NM_006238.5, NM_001171818.2, NM_177435.3
UniProt ID Q03181
Summary This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. The encoded protein is thought to function as an integrator of transcriptional repression and nuclear receptor signaling. It may inhibit the ligand-induced transcriptional activity of peroxisome proliferator activated receptors alpha and gamma, though evidence for this effect is inconsistent. Expression of this gene in colorectal cancer cells may be variable but is typically relatively low. Knockout studies in mice suggested a role for this protein in myelination of the corpus callosum, lipid metabolism, differentiation, and epidermal cell proliferation. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. provided by RefSeq, Aug 2017
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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