DUSP1 Human shRNA Plasmid Kit (Locus ID 1843)
Specifications
| Product Data | |
| Locus ID | 1843 |
|---|---|
| Synonyms | CL100; HVH1; MKP-1; MKP1; PTPN10 |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | DUSP1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 1843). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | NM_004417, NM_004417.1, NM_004417.2, NM_004417.3, BC022463, BC022463.1, NM_004417.4 |
| UniProt ID | P28562 |
| Summary | The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in several cellular processes. This protein appears to play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Finally, the encoded protein can make some solid tumors resistant to both chemotherapy and radiotherapy, making it a target for cancer therapy. provided by RefSeq, Aug 2017 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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