ABCA1 Human shRNA Plasmid Kit (Locus ID 19)

SKU
TG315036
ABCA1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
In Control Promo
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 19
Synonyms ABC-1; ABC1; CERP; HDLCQTL13; HDLDT1; HPALP1; TGD
Vector pGFP-V-RS
E. coli Selection Kanamycin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components ABCA1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 19). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq BC034824, NM_005502, NM_005502.1, NM_005502.2, NM_005502.3, BC146856, NM_005502.4
UniProt ID O95477
Summary The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency. provided by RefSeq, Sep 2019
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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