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ABCB7 Human shRNA Plasmid Kit (Locus ID 22)

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SKU
TG315028
ABCB7 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
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Specifications
Specifications
Product Data
Locus ID 22
Synonyms ABC7; ASAT; Atm1p; EST140535
Vector pGFP-V-RS
E. coli Selection Kanamycin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components ABCB7 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 22). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001271696, NM_001271697, NM_001271698, NM_001271699, NM_004299, NM_004299.1, NM_004299.2, NM_004299.3, NM_004299.4, NM_001271697.1, NM_001271698.1, NM_001271696.1, NM_001271699.1, BC006323, BC006323.2, NM_001271697.3, NM_001271698.3, NM_001271699.3, NM_004299.6, NM_001271696.3
UniProt ID O75027
Summary The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. provided by RefSeq, Nov 2012
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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