GBA Human shRNA Plasmid Kit (Locus ID 2629)

SKU
TG312830
GBA - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 2629
Synonyms GBA1; GCB; GLUC
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components GBA - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 2629). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_000157, NM_001005741, NM_001005742, NM_001005749, NM_001005750, NM_001171811, NM_001171812, NM_001005741.1, NM_001005741.2, NM_001005742.1, NM_001005742.2, NM_000157.1, NM_000157.2, NM_000157.3, NM_001171811.1, NM_001171812.1, NM_001005749.1, NM_001005750.1, BC003356, BC003356.1, NM_001005741.3, NM_001005742.3, NM_001171812.2, NM_000157.4
UniProt ID P04062
Summary This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jan 2010
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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