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CD49b (ITGA2) Human shRNA Plasmid Kit (Locus ID 3673)

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SKU
TG312097
ITGA2 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*

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Other products for "CD49b or NM_002203"

Specifications
Specifications
Product Data
Locus ID 3673
Synonyms BR; CD49B; GPIa; HPA-5; VLA-2; VLAA2
Vector pGFP-V-RS
E. coli Selection Kanamycin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components ITGA2 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 3673). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_002203, NR_073103, NR_073104, NR_073105, NR_073106, NR_073107, NM_002203.1, NM_002203.2, NM_002203.3, BC143505, BC143508, BC143509, BC143511, BC143512, BC148596, BC156715, BM828183, BM979113, NM_002203.4
UniProt ID P17301
Summary This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2012
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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Documents
Resources

file-alt Citations

CD49b inhibits osteogenic differentiation and plays an important role in osteosarcoma progression
Ren, Piperdi, Koirala et al
Oncotarget (2017) 8 (50), 87848-87859 DOI: 10.18632/oncotarget.21254
Snippet: Plasmids and lentivirus. Lenti cDNA clone of human CD49b (RC212617L1) and Lenti-Vpak lentiviral Packaging Kit (TR30022) were purchased from Origene (Rockville, MD) A CD49b human shRNA plasmid kit (TG312097) was purchased from Origene (Rockville, MD
FigureFigureFigure
Showing 1-1 of 1 papers.
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