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PFKFB3 Human shRNA Plasmid Kit (Locus ID 5209)

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SKU
TG310484
PFKFB3 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*

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Other products for "PFKFB3 or NM_001145443"

Specifications
Specifications
Product Data
Locus ID 5209
Synonyms iPFK-2; IPFK2; PFK2
Vector pGFP-V-RS
E. coli Selection Kanamycin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components PFKFB3 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 5209). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001145443, NM_001282630, NM_001314063, NM_001323016, NM_001323017, NM_004566, NR_136554, NM_004566.1, NM_004566.2, NM_004566.3, NM_001145443.1, NM_001145443.2, NM_001282630.1, NM_001282630.2, BC040482, BC040482.1, BC037258, BC042656, NM_001363545, NM_004566.4, NM_001145443.3
UniProt ID Q16875
Summary The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Apr 2016
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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