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ITCH Human shRNA Plasmid Kit (Locus ID 83737)

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TG303878
ITCH - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
In Control Promo
  $883.00
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Specifications
Specifications
Product Data
Locus ID 83737
Synonyms ADMFD; AIF4; AIP4; NAPP1
Vector pGFP-V-RS
E. coli Selection Kanamycin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components ITCH - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 83737). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001257137, NM_001257138, NM_031483, NM_001324197, NM_001324198, NM_031483.1, NM_031483.2, NM_031483.3, NM_031483.4, NM_031483.5, NM_031483.6, NM_001257138.1, NM_001257138.2, NM_001257137.1, NM_001257137.2, BC006848, BC011571, NM_001257137.3, NM_001257138.3, NM_031483.7
UniProt ID Q96J02
Summary This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. provided by RefSeq, Mar 2012
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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