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Pnpla2 Mouse shRNA Plasmid (Locus ID 66853)

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SKU
TF512624
Pnpla2 - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 66853
Synonyms 0610039C21Rik; 1110001C14Rik; Atgl; TTS-2.2
Vector pRFP-C-RS
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Pnpla2 - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 66853). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
RefSeq BC019188, BC044781, BC064747, NM_001163689, NM_025802, NR_028142, NM_001163689.1, NM_025802.1, NM_025802.2, NM_025802.3, BC019188.1, BC026807, BC034190, BC044737, BC054825
UniProt ID Q8BJ56
Summary Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets (PubMed:15550674). Also has acylglycerol transacylase activity. May act coordinately with LIPE/HLS within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes. May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Lipid droplet availability affects neural stem/progenitor cell metabolism and proliferation
Ramosaj, Madsen, Maillard et al
Nat Commun (2021) 12 (1), 7362 DOI: 10.1038/s41467-021-27365-7
Cited by 127
AI Summary: OriGene products contributed to this study by providing plasmids encoding shRNAs against Atgl and control shRNA (catalog number TF512624), which were used to manipulate gene expression and visualize transfected neural stem/progenitor cells, enabling investigation of lipid droplet function in cell metabolism and proliferation.
Snippet: … Plasmids encoding for shRNAs against Atgl or control shRNA were bought from Origene (TF512624). …Plasmids encoding for shRNAs against Atgl or control shRNA were bought from Origene (TF512624). …
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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