LYK5 (STRADA) Human shRNA Plasmid Kit (Locus ID 92335)
SKU
TF320748
STRADA - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
$883.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 92335 |
|---|---|
| Synonyms | LYK5; NY-BR-96; PMSE; Stlk; STRAD; STRAD alpha |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Format | Retroviral plasmids |
| Components | STRADA - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 92335). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_001003786, NM_001003787, NM_001003788, NM_001165969, NM_001165970, NM_153335, NM_153335.1, NM_153335.2, NM_153335.3, NM_153335.4, NM_153335.5, NM_001003788.1, NM_001003788.2, NM_001003786.1, NM_001003786.2, NM_001003787.1, NM_001003787.2, NM_001165970.1, NM_001165969.1, BC043641, NM_001363786, NM_001363787, NM_001363789, NM_001363790, NM_001363791, NM_001363788, NR_156741, NM_001003788.3, NM_001003787.4, NM_153335.6, NM_001165969.2, NM_001003786.3, NM_001165970.2 |
| UniProt ID | Q7RTN6 |
| Summary | The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a 'pseudokinase'. The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known. provided by RefSeq, Sep 2009 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.