AXL Human shRNA Plasmid Kit (Locus ID 558)

SKU
TF320269
AXL - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 558
Synonyms ARK; JTK11; Tyro7; UFO
Vector pRFP-C-RS
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components AXL - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 558). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
RefSeq NM_001278599, NM_001699, NM_021913, NM_021913.1, NM_021913.2, NM_021913.3, NM_021913.4, NM_001699.1, NM_001699.2, NM_001699.3, NM_001699.4, NM_001699.5, NM_001278599.1, BC032229, BC032229.1, NM_001699.6, NM_021913.5
UniProt ID P30530
Summary The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. provided by RefSeq, Jul 2013
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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