OriGene Logo

ULK3 Human shRNA Plasmid Kit (Locus ID 25989)

Be the first to review this product
SKU
TF317070
DKFZP434C131 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
  $883.00
In Stock*

Frequently Bought Together (2)

TA326685 Rabbit Polyclonal ULK3 Antibody
100 ug
$640.00
TF81001 TurboFectin Transfection Reagent (1 mL in 1 vial)
1 ml in 1 vial
$530.00

Other products for "ULK3 or NM_001099436"

Specifications
Specifications
Product Data
Locus ID 25989
Vector pRFP-C-RS
E. coli Selection Chloramphenicol (34 ug/ml)
Format Retroviral plasmids
Components DKFZP434C131 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 25989). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
RefSeq NM_001099436, NM_001284364, NM_001284365, NM_015518, NR_104307, NR_104308, NR_104309, NM_001099436.1, NM_001099436.2, NM_001099436.3, NM_001284365.1, NM_001284365.2, NM_001284364.1, NM_001284364.2, NM_015518.1, BC036117, BC048289, BC056423, BC157884, NM_001284364.3, NM_001099436.4, NM_001284365.3
UniProt ID Q6PHR2
Summary Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Shipping Ambient
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Documents
Resources

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.