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Apolipoprotein E (APOE) Human shRNA Plasmid Kit (Locus ID 348)

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SKU
TF314721
APOE - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 348
Synonyms AD2; APO-E; ApoE4; LDLCQ5; LPG
Vector pRFP-C-RS
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components APOE - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 348). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
RefSeq NM_000041, NM_001302688, NM_001302689, NM_001302690, NM_001302691, NM_000041.1, NM_000041.2, NM_000041.3, NM_001302689.1, NM_001302690.1, NM_001302691.1, NM_001302688.1, BC003557, BC003557.1, BM042032, NM_001302688.2, NM_000041.4, NM_001302689.2, NM_001302691.2
UniProt ID P02649
Summary The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. provided by RefSeq, Jun 2016
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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