CAPNS1 Human shRNA Plasmid Kit (Locus ID 826)
Specifications
| Product Data | |
| Locus ID | 826 |
|---|---|
| Synonyms | CALPAIN4; CANP; CANPS; CAPN4; CDPS; CSS1 |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | CAPNS1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 826). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_001003962, NM_001302632, NM_001302633, NM_001749, NM_001003962.2, NM_001749.1, NM_001749.2, NM_001749.3, NM_001302633.1, NM_001302632.1, BC018931, BC018931.2, BC000592, BC007779, BC011903, BC017308, BC021933, BC023643, BC064998, NM_001749.4, NM_001003962.3, NM_001302632.2, NM_001302633.2 |
| UniProt ID | P04632 |
| Summary | This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. provided by RefSeq, Oct 2014 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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