CAPNS1 Rabbit Polyclonal Antibody

SKU
TA323500
Anti-CAPNS1 Rabbit Polyclonal Antibody
  $305.00
In Stock*
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Specifications
Specifications
Product Data
Application IHC, WB
Recommended Dilution WB: 500-2000
WB positive control: K562 and NIH/3T3 cells
IHC: 50-200
Positive control: Human ovarian cancer
Predicted cell location: Cytoplasm
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein corresponding to a region derived from 91-268 amino acids of human calpain, small subunit 1
Buffer PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 28 kDa
Gene Name calpain small subunit 1
Database Link
Background Calpains are a ubiquitous; well-conserved family of calcium-dependent; cysteine proteases. Calpain families have been implicated in neurodegenerative processes; as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits; all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.
Synonyms CALPAIN4; CANP; CANPS; CAPN4; CDPS; CSS1
Reference Data
Protein Categories Intracellular Proteins
Protein Families Druggable Genome, Protease
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