GPNMB Human shRNA Plasmid Kit (Locus ID 10457)

SKU TF312675

GPNMB - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided

Product Data

• Locus ID: 10457
• Synonyms: HGFIN; NMB; PLCA3
• Vector: pRFP-C-RS
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Retroviral plasmids
• Components: GPNMB - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 10457). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
• RefSeq: BC011595, NM_001005340, NM_002510, NM_001005340.1, NM_002510.1, NM_002510.2, BC011595.1, BC032783, BC032783.1, BC025297, BM750843, NM_002510.3
• UniProt ID: Q14956
• Summary: The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient