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CD51 (ITGAV) Human shRNA Plasmid Kit (Locus ID 3685)

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TF312085
ITGAV - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
  $883.00
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Specifications
Specifications
Product Data
Locus ID 3685
Synonyms CD51; MSK8; VNRA; VTNR
Vector pRFP-C-RS
E. coli Selection Chloramphenicol (34 ug/ml)
Format Retroviral plasmids
Components ITGAV - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 3685). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
RefSeq NM_001144999, NM_001145000, NM_002210, NM_002210.1, NM_002210.3, NM_002210.4, NM_001144999.1, NM_001144999.2, NM_001145000.1, NM_001145000.2, BC047454, BC072686, BC126231, BC136442, BC144100
UniProt ID P06756
Summary The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. provided by RefSeq, Oct 2015
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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