BMP4 Human shRNA Plasmid Kit (Locus ID 652)
Specifications
| Product Data | |
| Locus ID | 652 |
|---|---|
| Synonyms | BMP2B; BMP2B1; MCOPS6; OFC11; ZYME |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | BMP4 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 652). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_001202, NM_130850, NM_130851, NM_001347912, NM_001347913, NM_001347914, NM_001347915, NM_001347916, NM_001347917, NM_001202.1, NM_001202.2, NM_001202.3, NM_001202.4, NM_001202.5, NM_130850.1, NM_130850.2, NM_130850.3, NM_130850.4, NM_130851.1, NM_130851.2, NM_130851.3, BC020546, BC020546.2 |
| UniProt ID | P12644 |
| Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. provided by RefSeq, Jul 2016 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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