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BMP4 Mouse Monoclonal Antibody [Clone ID: OTI6B7]

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SKU
TA500014
Anti-BMP4 mouse monoclonal antibody, clone OTI6B7 (formerly 6B7)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
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View other "BMP4 or NM_130850" antibodies

Specifications
Specifications
Product Data
Clone Name OTI6B7
Application IF, WB
Recommended Dilution WB 1:500, IF 1:100
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Recombinant fragment expressed in E.coli corresponding to amino acids 293-408 of human BMP4
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 0.42 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 46.4 kDa
Gene Name bone morphogenetic protein 4
Database Link
Background BMP4 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva.
Synonyms BMP2B; BMP2B1; MCOPS6; OFC11; ZYME
Reference Data
Protein Categories Cytokines, Growth Factors, Intracellular Proteins, Secreated Proteins
Protein Families Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, Induced pluripotent stem cells, Secreted Protein, Stem cell relevant signaling - TGFb/BMP signaling pathway
Protein Pathways Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer, TGF-beta signaling pathway
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Other "OTI6B7" antibodies (4)
SKU Description Size Price
CF500014 Carrier-free (BSA/glycerol-free) BMP4 mouse monoclonal antibody, clone OTI6B7 (formerly 6B7) 100 ug
$620.00
TA500014AM Anti-BMP4 mouse monoclonal antibody, clone OTI6B7 (formerly 6B7), Biotinylated 100 ul
$509.00
TA500014BM Anti-BMP4 mouse monoclonal antibody, clone OTI6B7 (formerly 6B7), HRP conjugated 100 ul
$509.00
TA500014S Anti-BMP4 mouse monoclonal antibody, clone OTI6B7 (formerly 6B7) 30 ul
$200.00

file-alt Citations

Spatial Stem Cell Fate Engineering via Facile Morphogen Localization
Jin, Floy, Simmons et al
Adv Healthc Mater (2021)
Cited by 2
AI Summary: OriGene's BMP4 antibody (TA500014) was used to detect and confirm the spatial localization of BMP4 morphogen on patterned substrates, enabling precise control of stem cell differentiation in the study.
Snippet: Briefly, BMP-patterned plate was incubated in goat serum (10%) for 1 h at room temperature and incubated in BMP4 antibody (OriGene, TA500014) diluted in 10% goat serum (1:100 dilution) overnight at 4 ℃. On the next day, the surface was rinsed with PBS three times
Anti-Leukemia Effects of Notch-Mediated Inhibition of Oncogenic PLK1 in B-Cell Acute Lymphoblastic Leukemia
Kannan, Aitken, Herbrich et al
Mol. Cancer Ther. (2019)
AI Summary: In this study, the OriGene HES1 antibody (TA500014) was used to investigate the molecular mechanisms underlying Notch-mediated inhibition of PLK1 in B-cell acute lymphoblastic leukemia.
Snippet: Studies Hybridoma Bank, University of Iowa, Iowa City, IA), HES1 (ab71559;AbCam, Cambridge, MA;TA500014, Origene, Rockville, MD), Notch-1, -3, and-4(ab52627, ab23426, and ab184742, Abcam), Jagged1 (sc11376;Santa Cruz Biotechnology), DLL1 (sc73899
Showing 1-2 of 2 papers.
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