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REST (NM_005612) Human Recombinant Protein

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SKU
TP762777
Purified recombinant protein of Human RE1-silencing transcription factor (REST), transcript variant 1, Pro798-Glu1097, with N-terminal His tag, expressed in E.coli, 50ug
Size:
50 ug
  $270.00
In Stock*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding the region (Pro798-Glu1097) of REST
Tag N-terminal His tag
Predicted MW 35.0 kDa
Concentration >100 ug/mL as determined by microplate Bradford method
Purity > 90% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8M Urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Stability Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_005603
Locus ID 5978
UniProt ID Q13127
Cytogenetics 4q12
RefSeq Size 7333
RefSeq ORF 3291
Synonyms DFNA27; GINGF5; HGF5; NRSF; WT6; XBR
Summary This gene was initially identified as a transcriptional repressor that represses neuronal genes in non-neuronal tissues. However, depending on the cellular context, this gene can act as either an oncogene or a tumor suppressor. The encoded protein is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regulator of neurogenesis. Alternatively spliced transcript variants have been described. provided by RefSeq, May 2018
Protein Categories Cancer: Bladder, Intracellular Proteins, Nervous system Diseases, Transciption Factors
Protein Families Transcription Factors
Protein Pathways Huntington's disease
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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