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Rubicon (RUBCN) (NM_014687) Human Recombinant Protein

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SKU
TP762693
Purified recombinant protein of Human KIAA0226 (KIAA0226), transcript variant 2, full length, with N-GST and C-His tag, expressed in E.coli, 50ug
Size:
50 ug
  $270.00
In Stock*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding the region full length of KIAA0226
Tag N-GST and C-HIS
Predicted MW 136.6 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_055502
Locus ID 9711
UniProt ID Q92622 Q8N4U6
Cytogenetics 3q29
RefSeq Size 6732
RefSeq ORF 2916
Synonyms KIAA0226; RUBICON; SCAR15
Summary The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. provided by RefSeq, Apr 2014
Protein Categories Intracellular Proteins, Nervous system: Neurodegenerative diseases
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Other "Rubicon" proteins (4)
SKU Description Size Price
PH320593 KIAA0226 MS Standard C13 and N15-labeled recombinant protein (NP_055502) 10 ug
$3,360.00
LC415105 Lyophilized KIAA0226 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY415105 Transient overexpression lysate of KIAA0226 (KIAA0226), transcript variant 2 (as WB positive control) 100 ug
$665.00
TP320593 Purified recombinant protein of Homo sapiens KIAA0226 (KIAA0226), transcript variant 2, 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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