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IL3RA (NM_002183) Human Recombinant Protein

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SKU
TP762389
Purified recombinant protein of Human interleukin 3 receptor, alpha (low affinity) (IL3RA), Thr19-Arg305, with N-terminal His tag, expressed in E.coli, 50ug
Size:
50 ug
  $260.00
In Stock*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding the region (Thr19-Arg305) of IL3RA
Tag N-His
Predicted MW 33.1 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity >80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_002174
Locus ID 3563
UniProt ID P26951
Cytogenetics X;Y
RefSeq Size 1726
RefSeq ORF 1134
Synonyms CD123; hIL-3Ra; IL3R; IL3RAY; IL3RX; IL3RY
Summary The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. provided by RefSeq, Jun 2012
Protein Categories ADC Targets, CAR-T Targets, CD Markers, Cytokines, Intracellular Proteins, Membrane Proteins
Protein Families Transmembrane
Protein Pathways Apoptosis, Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway
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Other "IL3RA" proteins (5)
SKU Description Size Price
PH306420 IL3RA MS Standard C13 and N15-labeled recombinant protein (NP_002174) 10 ug
$3,360.00
LC419481 Lyophilized IL3RA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY419481 Transient overexpression lysate of interleukin 3 receptor, alpha (low affinity) (IL3RA) (as WB positive control) 100 ug
$436.00
TP306420 Recombinant protein of human interleukin 3 receptor, alpha (low affinity) (IL3RA), 20 µg 20 ug
$867.00
TP723926 Recombinant human CD123 protein with C-terminal human Fc and 6×His tag 100 ug
$770.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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