IL3RA Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Human Fc and 6×His Tag |
| Predicted MW | The protein has a predicted molecular mass of 80-90 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Buffer | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization |
| Reconstitution Method | 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube. 2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000 3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL) 4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample. |
| Preparation | Affinity purification |
| Recommended Dilution | ELISA |
| Storage | Store the lyophilized protein at -20°C. After reconstitution, store the protein at -80°C for 12 months. Avoid repeated freezing and thawing. |
| Stability | 12 months from date of despatch |
| Shipping | Ambient |
| Reference Data | |
| Locus ID | 3563 |
| UniProt ID | P26951 |
| Synonyms | IL3R;IL3RA;IL-3Ra;IL-3R-alpha;IL3RAY;IL3RX;IL3RY;CD123 antigen;CD123;hIL3Ra;hIL-3Ra;MGC34174;IL-3 R alpha |
| Summary | Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor a chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells |
| Protein Categories | ADC Targets, CAR-T Targets, CD Markers, Cytokines, Intracellular Proteins, Membrane Proteins |
| Protein Families | ELISA |
| Protein Pathways | Apoptosis, Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "IL3RA" proteins (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH306420 | IL3RA MS Standard C13 and N15-labeled recombinant protein (NP_002174) | 10 ug |
$3,360.00
|
|
| LC419481 | Lyophilized IL3RA HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY419481 | Transient overexpression lysate of interleukin 3 receptor, alpha (low affinity) (IL3RA) (as WB positive control) | 100 ug |
$436.00
|
|
| TP306420 | Recombinant protein of human interleukin 3 receptor, alpha (low affinity) (IL3RA), 20 µg | 20 ug |
$867.00
|
|
| TP762389 | Purified recombinant protein of Human interleukin 3 receptor, alpha (low affinity) (IL3RA), Thr19-Arg305, with N-terminal His tag, expressed in E.coli, 50ug | 50 ug |
$260.00
|
|
Citations
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.