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ErbB 4 (ERBB4) (NM_005235) Human Recombinant Protein

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SKU
TP762049
Purified recombinant protein of Human v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) (ERBB4), transcript variant JM-a/CVT-1,Arg992-End, with N-terminal His tag, expressed in E. coli, 50ug
Size:
50 ug
  $270.00
In Stock*
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding the region(Arg992-End) of ERBB4
Tag N-His
Predicted MW 35.9 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_005226
Locus ID 2066
UniProt ID Q15303
Cytogenetics 2q34
RefSeq Size 5484
RefSeq ORF 3924
Synonyms ALS19; HER4; p180erbB4
Summary This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. provided by RefSeq, Jul 2008
Protein Categories Enzyme: Kinases, Growth Factors, Intracellular Proteins, Membrane Proteins, Nervous system: Neurodegenerative diseases
Protein Families Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways Calcium signaling pathway, Endocytosis, ErbB signaling pathway
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Other "ERBB4" proteins (9)
SKU Description Size Price
PH320500 ERBB4 MS Standard C13 and N15-labeled recombinant protein (NP_001036064) 10 ug
$3,360.00
LC401604 Lyophilized ERBB4 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC421001 Lyophilized ERBB4 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401604 Transient overexpression lysate of v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) (ERBB4), transcript variant JM-a/CVT-1 (as WB positive control) 100 ug
$665.00
LY421001 Transient overexpression lysate of v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) (ERBB4), transcript variant JM-a/CVT-2 (as WB positive control) 100 ug
$665.00
TP320500 Recombinant protein of human v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) (ERBB4), transcript variant JM-a/CVT-2, 20 µg 20 ug
$737.00
TP700108 Purified recombinant protein of human v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) (ERBB4), with C-terminal DDK/His tag, expressed in human cells, 20 µg 20 ug
$900.00
TP710090 Recombinant protein of human v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) (ERBB4), transcript variant JM-a/CVT-2, full length, with C-terminal DDK tag, expressed in sf9, 20ug 20 ug
$540.00
TP710093 Recombinant protein of human v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) (ERBB4), transcript variant JM-a/CVT-2, residues 26-651, with C-terminal DDK tag, expressed in sf9, 20ug 20 ug
$540.00

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