ErbB 4 (ERBB4) Mouse Monoclonal Antibody [Clone ID: OTI1H6]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI1H6 |
|---|---|
| Application | IHC, WB |
| Recommended Dilution | IHC 1:1000 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 992-1308 of human ERBB4 (NP_005226) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 144.2 kDa |
| Gene Name | erb-b2 receptor tyrosine kinase 4 |
| Database Link | |
| Background | This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. provided by RefSeq, Jul 2008 |
| Synonyms | ALS19; HER4; p180erbB4 |
| Reference Data | |
| Protein Categories | Enzyme: Kinases, Growth Factors, Intracellular Proteins, Membrane Proteins, Nervous system: Neurodegenerative diseases |
| Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
| Protein Pathways | Calcium signaling pathway, Endocytosis, ErbB signaling pathway |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI1H6" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF804606 | Carrier-free (BSA/glycerol-free) ERBB4 mouse monoclonal antibody, clone OTI1H6 | 100 ug |
$620.00
|
|
| TA804606AM | ERBB4 mouse monoclonal antibody,clone OTI1H6, Biotinylated | 100 ul |
$509.00
|
|
| TA804606BM | ERBB4 mouse monoclonal antibody,clone OTI1H6, HRP conjugated | 100 ul |
$509.00
|
|
| TA804606S | ERBB4 mouse monoclonal antibody,clone OTI1H6 | 30 ul |
$200.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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