ErbB 4 (ERBB4) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1H6]

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SKU
TA804606AM
ERBB4 mouse monoclonal antibody,clone OTI1H6, Biotinylated
  $509.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Clone Name OTI1H6
Application IHC, WB
Recommended Dilution IHC 1:1000
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 992-1308 of human ERBB4 (NP_005226) produced in E.coli.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Biotin
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 144.2 kDa
Gene Name erb-b2 receptor tyrosine kinase 4
Database Link
Background This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. provided by RefSeq, Jul 2008
Synonyms ALS19; HER4; p180erbB4
Reference Data
Protein Categories Enzyme: Kinases, Growth Factors, Intracellular Proteins, Membrane Proteins, Nervous system: Neurodegenerative diseases
Protein Families Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways Calcium signaling pathway, Endocytosis, ErbB signaling pathway
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Other "OTI1H6" antibodies (4)
SKU Description Size Price
CF804606 Carrier-free (BSA/glycerol-free) ERBB4 mouse monoclonal antibody, clone OTI1H6 100 ug
$620.00
TA804606 ERBB4 mouse monoclonal antibody,clone OTI1H6 100 ul
$447.00
TA804606BM ERBB4 mouse monoclonal antibody,clone OTI1H6, HRP conjugated 100 ul
$509.00
TA804606S ERBB4 mouse monoclonal antibody,clone OTI1H6 30 ul
$200.00

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