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PITX2 (NM_000325) Human Recombinant Protein

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SKU
TP761309
Purified recombinant protein of Human paired-like homeodomain 2 (PITX2), transcript variant 3, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Size:
50 ug
  $270.00
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length PITX2
Tag N-GST and C-His
Predicted MW 61.6 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_000316
Locus ID 5308
UniProt ID Q99697
Cytogenetics 4q25
RefSeq Size 2337
RefSeq ORF 972
Synonyms ARP1; ASGD4; Brx1; IDG2; IGDS; IGDS2; IHG2; IRID2; Otlx2; PTX2; RGS; RIEG; RIEG1; RS
Summary This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described. provided by RefSeq, Jul 2008
Protein Categories Intracellular Proteins, Nervous system Diseases, Transciption Factors
Protein Families Transcription Factors
Protein Pathways TGF-beta signaling pathway
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Other "PITX2" proteins (9)
SKU Description Size Price
LC400123 Lyophilized PITX2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC407091 Lyophilized PITX2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC407092 Lyophilized PITX2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400123 Transient overexpression lysate of paired-like homeodomain 2 (PITX2), transcript variant 3 (as WB positive control) 100 ug
$436.00
LY407091 Transient overexpression lysate of paired-like homeodomain 2 (PITX2), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY407092 Transient overexpression lysate of paired-like homeodomain 2 (PITX2), transcript variant 1 (as WB positive control) 100 ug
$436.00
TP760239 Recombinant protein of human paired-like homeodomain 2 (PITX2), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug 50 ug
$270.00
TP760287 Recombinant protein of human paired-like homeodomain 2 (PITX2), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug 50 ug
$270.00
TP761571 Purified recombinant protein of Human paired-like homeodomain 2 (PITX2), transcript variant 2, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug 50 ug
$270.00

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