PITX2 Mouse Monoclonal Antibody [Clone ID: OTI1H10]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI1H10 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:2000 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1-200 of human PITX2 (NP_700475) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 35.2 kDa |
| Gene Name | paired like homeodomain 2 |
| Database Link | |
| Background | This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described. provided by RefSeq, Jul 2008 |
| Synonyms | ARP1; Brx1; IDG2; IGDS; IGDS2; IHG2; IRID2; Otlx2; PTX2; RGS; RIEG; RIEG1; RS |
| Reference Data | |
| Protein Categories | Intracellular Proteins, Nervous system Diseases, Transciption Factors |
| Protein Families | Transcription Factors |
| Protein Pathways | TGF-beta signaling pathway |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI1H10" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF809670 | Carrier-free (BSA/glycerol-free) PITX2 mouse monoclonal antibody,clone OTI1H10 | 100 ug |
$620.00
|
|
| TA809670AM | PITX2 mouse monoclonal antibody,clone OTI1H10, Biotinylated | 100 ul |
$509.00
|
|
| TA809670BM | PITX2 mouse monoclonal antibody,clone OTI1H10, HRP conjugated | 100 ul |
$509.00
|
|
| TA809670S | PITX2 mouse monoclonal antibody,clone OTI1H10 | 30 ul |
$200.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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