REA (PHB2) (NM_007273) Human Recombinant Protein

SKU
TP761198
Purified recombinant protein of Human prohibitin 2 (PHB2), transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
  $270.00
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length PHB2
Tag N-His
Predicted MW 33.1 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_009204
Locus ID 11331
UniProt ID Q99623
Cytogenetics 12p13.31
RefSeq Size 1457
RefSeq ORF 897
Synonyms BAP; Bap37; BCAP37; p22; PNAS-141; REA
Summary Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. In mitochondria, regulates cytochrome-c oxidase assembly (COX) and mitochondrial respiration. Binding to sphingoid 1-phosphate (SPP) modulates its regulator activity (PubMed:20959514).UniProtKB/Swiss-Prot Function
Protein Families Druggable Genome, Transcription Factors
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Other "REA" proteins (5)
SKU Description Size Price
LC402126 Lyophilized PHB2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC428526 Lyophilized PHB2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY402126 Transient overexpression lysate of prohibitin 2 (PHB2), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY428526 Transient overexpression lysate of prohibitin 2 (PHB2), transcript variant 1 (as WB positive control) 100 ug
$436.00
TP760501 Purified recombinant protein of Human prohibitin 2 (PHB2), transcript variant 1, with N-terminal HIS tag, expressed in E.Coli, 50ug 50 ug
$270.00

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