E2F3 (NM_001949) Human Recombinant Protein

CAT#: TP760363

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Purified recombinant protein of Human E2F transcription factor 3 (E2F3), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug


 Product Datasheet for 'TP760363'

 Cited in 1 publication.

  View other "E2F3" proteins (2)

USD 205.00


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    • 50 ug


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Product Data
Description Purified recombinant protein of Human E2F transcription factor 3 (E2F3), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Species Human
Expression Host E. coli
Tag N-His
Predicted MW 49 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl
Bioactivity WB standard (PMID: 26639898)
Reference Data
RefSeq NP_001940
Locus ID 1871
Refseq Size 4744
Cytogenetics 6p22.3
Refseq ORF 1395
Synonyms E2F-3
Summary This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are pseudogenes for this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Bladder cancer, Cell cycle, Chronic myeloid leukemia, Glioma, Melanoma, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Prostate cancer, Small cell lung cancer

Citations (1)

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