alpha Synuclein (SNCA) (NM_000345) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | Tag Free |
| Predicted MW | 14.3 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 95% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | PBS, pH 7.4 |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_000336 |
| Locus ID | 6622 |
| UniProt ID | P37840 |
| Cytogenetics | 4q22.1 |
| RefSeq Size | 1543 |
| RefSeq ORF | 420 |
| Synonyms | NACP; PARK1; PARK4; PD1 |
| Summary | Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. provided by RefSeq, Feb 2016 |
| Protein Categories | Growth Factors, Intracellular Proteins, Nervous system: Neurodegenerative diseases |
| Protein Families | Druggable Genome |
| Protein Pathways | Alzheimer's disease, Parkinson's disease |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "alpha Synuclein" proteins (16)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH310606 | SNCA MS Standard C13 and N15-labeled recombinant protein (NP_000336) | 10 ug |
$3,360.00
|
|
| PH321446 | SNCA MS Standard C13 and N15-labeled recombinant protein (NP_009292) | 10 ug |
$3,360.00
|
|
| LC400127 | Lyophilized SNCA HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC416080 | Lyophilized SNCA HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC431763 | Lyophilized SNCA HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC431764 | Lyophilized SNCA HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400127 | Transient overexpression lysate of synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY416080 | Transient overexpression lysate of synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant 4 (as WB positive control) | 100 ug |
$436.00
|
|
| LY431763 | Transient overexpression lysate of synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY431764 | Transient overexpression lysate of synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant 3 (as WB positive control) | 100 ug |
$436.00
|
|
| TP310606 | Recombinant protein of human synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant NACP140, 20 µg | 20 ug |
$867.00
|
|
| TP321446 | Recombinant protein of human synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant NACP112, 20 µg | 20 ug |
$867.00
|
|
| TP328735 | Recombinant protein of human synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant 2, 20 µg | 20 ug |
$867.00
|
|
| TP328736 | Recombinant protein of human synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant 3, 20 µg | 20 ug |
$867.00
|
|
| TP720923 | Purified recombinant protein of Human synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant 1 | 10 ug |
$160.00
|
|
| TP721177 | Purified recombinant protein of Human synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant 1 | 10 ug |
$190.00
|
|
Citations
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