BMP2 (NM_001200) Human Recombinant Protein
$540.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | Tag Free |
| Predicted MW | 13 kDa |
| Concentration | Resuspend the protein to the desired concentration in proper buffer. |
| Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | Lyophilized from a sterile solution containing 10 mM sodium citrate, pH 3.5 |
| Bioactivity | Measured?by?its?ability?to?induce?alkaline?phosphatase?production in?ATDC5?cells. ED50 for this effect is typically 36 - 55 ng/ml. Co-immunoprecipitation (PMID: 28009989) |
| Endotoxin | < 0.1 EU per 1 µg of the protein by the LAL |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NP_001191 |
| Locus ID | 650 |
| UniProt ID | P12643 |
| Cytogenetics | 20p12.3 |
| RefSeq Size | 1547 |
| RefSeq ORF | 1188 |
| Synonyms | BDA2; BMP2A; SSFSC; SSFSC1 |
| Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. provided by RefSeq, Jul 2016 |
| Protein Categories | Cytokines, Growth Factors, Secreated Proteins |
| Protein Families | Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Secreted Protein, Stem cell relevant signaling - TGFb/BMP signaling pathway, Transmembrane |
| Protein Pathways | Acute myeloid leukemia, Basal cell carcinoma, Cytokine-cytokine receptor interaction, Endocytosis, Hedgehog signaling pathway, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer, TGF-beta signaling pathway |
Reviews
Documents
| FAQs |
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Resources
| Recombinant Protein Resources |
Other "BMP2" proteins (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC400481 | BMP2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400481 | Transient overexpression lysate of bone morphogenetic protein 2 (BMP2) | 100 ug |
$436.00
|
|
| TP720011 | Recombinant protein of human bone morphogenetic protein 2 (BMP2), the domain of Gln283-Arg396 | 10 ug |
$340.00
|
|
| TP760521 | Purified recombinant protein of Human bone morphogenetic protein 2 (BMP2), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug | 50 ug |
$270.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.