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BMP2 (NM_001200) Human Recombinant Protein

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SKU
TP720011
Recombinant protein of human bone morphogenetic protein 2 (BMP2), the domain of Gln283-Arg396
Size:
10 ug 500 ug 50 ug 1 mg
  $340.00
7 Weeks*
Bulk/Customize

Frequently Bought Together (1)

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100 ul
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
Gln283-Arg396
Tag Tag Free
Predicted MW 13 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 um filtered solution of 10mM HAc-NH4Ac, 4% D-Mannitol, pH4.0.
Bioactivity ED50 is less than 50 ng/ml as determined by the cytolysis of MC3T3-E1 cells. Specific Activity of 2.0 x 104 IU/mg
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Reconstitution Method Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in 50mM Acetic Acid. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Shipping Ambient
Reference Data
RefSeq NP_001191
Locus ID 650
UniProt ID P12643
Cytogenetics 20p12.3
Synonyms BDA2; BMP2A; SSFSC; SSFSC1
Summary This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. provided by RefSeq, Jul 2016
Protein Categories Cytokines, Growth Factors, Secreated Proteins
Protein Families Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Secreted Protein, Stem cell relevant signaling - TGFb/BMP signaling pathway, Transmembrane
Protein Pathways Acute myeloid leukemia, Basal cell carcinoma, Cytokine-cytokine receptor interaction, Endocytosis, Hedgehog signaling pathway, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer, TGF-beta signaling pathway
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Documents
Resources
Other "BMP2" proteins (4)
SKU Description Size Price
LC400481 Lyophilized BMP2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400481 Transient overexpression lysate of bone morphogenetic protein 2 (BMP2) (as WB positive control) 100 ug
$436.00
TP750012 Recombinant protein of human Bone Morphogenetic Protein-2 (BMP2) produced in E. coli. 20 ug
$540.00
TP760521 Purified recombinant protein of Human bone morphogenetic protein 2 (BMP2), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug 50 ug
$270.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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