TIGIT Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Mouse Fc Tag |
| Predicted MW | The protein has a predicted molecular mass of 39.24 kDa after removal of the signal peptide.The apparent molecular mass of TIGIT-mFc is approximately 40-53 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Buffer | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization |
| Reconstitution Method | 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube. 2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000 3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL) 4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample. |
| Preparation | Affinity purification |
| Recommended Dilution | ELISA |
| Storage | Store the lyophilized protein at -20°C. After reconstitution, store the protein at -80°C for 12 months. Avoid repeated freezing and thawing. |
| Stability | 12 months from date of despatch |
| Shipping | Ambient |
| Reference Data | |
| Locus ID | 201633 |
| UniProt ID | Q495A1 |
| Synonyms | TIGIT;VSIG9;VSTM3 |
| Summary | This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity, this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses. |
| Protein Categories | ADC Targets, Membrane Proteins |
| Protein Families | ELISA |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "TIGIT" proteins (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH321447 | TIGIT MS Standard C13 and N15-labeled recombinant protein (NP_776160) | 10 ug |
$3,360.00
|
|
| LC406575 | Lyophilized TIGIT HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY406575 | Transient overexpression lysate of T cell immunoreceptor with Ig and ITIM domains (TIGIT) (as WB positive control) | 100 ug |
$436.00
|
|
| TP321447 | Recombinant protein of human T cell immunoreceptor with Ig and ITIM domains (TIGIT), 20 µg | 20 ug |
$737.00
|
|
| TP700214 | Purified recombinant protein of human T cell immunoreceptor with Ig and ITIM domains (TIGIT), with C-terminal DDK/His tag, expressed in human cells, 20 µg | 20 ug |
$900.00
|
|
| TP723994 | Recombinant human TIGIT Protein with C-terminal human Fc tag | 100 ug |
$825.00
|
|
| TP724033 | Recombinant human TIGIT Protein with C-terminal His tag | 100 ug |
$770.00
|
|
Citations
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