B7-1 (CD80) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Human Fc Tag |
| Predicted MW | The protein has a predicted molecular mass of 50.0 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Buffer | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization |
| Reconstitution Method | 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube. 2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000 3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL) 4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample. |
| Preparation | Affinity purification |
| Recommended Dilution | ELISA, Flow Cyt |
| Storage | Store the lyophilized protein at -20°C. After reconstitution, store the protein at -80°C for 12 months. Avoid repeated freezing and thawing. |
| Stability | 12 months from date of despatch |
| Shipping | Ambient |
| Reference Data | |
| Locus ID | 941 |
| UniProt ID | P33681 |
| Synonyms | CD80;B7;B7-1;B7.1;BB1;CD28LG;CD28LG1;LAB7 |
| Summary | The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. |
| Protein Categories | CD Markers, Cytokines, Intracellular Proteins, Membrane Proteins |
| Protein Families | ELISA, Flow Cyt |
| Protein Pathways | Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Type I diabetes mellitus, Viral myocarditis |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "B7-1" proteins (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH306540 | CD80 MS Standard C13 and N15-labeled recombinant protein (NP_005182) | 10 ug |
$3,360.00
|
|
| TP306540 | Recombinant protein of human CD80 molecule (CD80), 20 µg | 20 ug |
$867.00
|
|
| TP700242 | Purified recombinant protein of human CD80 molecule (CD80), with C-terminal Fc/His tag, expressed in human cells, 20 µg | 20 ug |
$900.00
|
|
| TP700243 | Purified recombinant protein of human CD80 molecule (CD80), with C-terminal DDK/His tag, expressed in human cells, 20 µg | 20 ug |
$900.00
|
|
Citations
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