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CD153 (TNFSF8) Human Recombinant Protein

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SKU
TP723961
Recombinant human CD30 Ligand Protein with N-terminal mouse Fc and C-terminal 6×His tag
Size:
100 ug
  $795.00
4 Weeks*
Bulk/Customize

Frequently Bought Together (1)

TA358538 TNFSF8 Antibody - N-terminal region
100 ul
$585.00

Other products for "CD153"

Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
mFc(Pro99-Lys330) CD30 Ligand(Gln63-Asp234) 6×His
Tag N-Mouse Fc and C-6×His Tag
Predicted MW The protein has a predicted molecular mass of 48.0 kDa after removal of the signal peptide.The apparent molecular mass of mFc-CD30 Ligand-His is approximately 53-70 kDa due to glycosylation.
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Buffer Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization
Reconstitution Method 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube.
2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000
3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL)
4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample.
Preparation Affinity purification
Recommended Dilution ELISA
Storage Store the lyophilized protein at -20°C.
After reconstitution, store the protein at -80°C for 12 months.
Avoid repeated freezing and thawing.
Stability 12 months from date of despatch
Shipping Ambient
Reference Data
Locus ID 944
UniProt ID P32971
Synonyms CD30-L;CD153;TNFSF8;CD30L;CD30LG;CD153 antigen;CD30 antigen ligand;CD30 Ligand
Summary The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30 lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene.
Protein Categories CD Markers, Cytokines, Membrane Proteins
Protein Families ELISA
Protein Pathways Cytokine-cytokine receptor interaction
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Documents
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Other "CD153" proteins (4)
SKU Description Size Price
PH311276 TNFSF8 MS Standard C13 and N15-labeled recombinant protein (NP_001235) 10 ug
$3,360.00
LC420051 Lyophilized TNFSF8 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY420051 Transient overexpression lysate of tumor necrosis factor (ligand) superfamily, member 8 (TNFSF8) (as WB positive control) 100 ug
$436.00
TP311276 Recombinant protein of human tumor necrosis factor (ligand) superfamily, member 8 (TNFSF8), 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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